BioXene

Key Features of BioXene’s Nanobiosensors

Auto-sensing – does not require sample preparation, labeling or washing.
Simplicity - one step mix and measure detection eliminates the need for trained technician.
In-solution detection - expands potential applications (medical imaging and in vivo diagnostics).
Ability to detect peptides, proteins, antibodies, antigens, and nucleic acids.
Low overhead costs and uses inexpensive laboratory equipment.
Portable - onsite detection.
Rapid – results in under an hour (no sample preparation required).
Targeted detection – specificity on par with ELISA tests.
Lower human error rate – efficient process reduces errors caused by technician mishandling.
Affordable – sensors will be cost competitive with existing ELISA tests.
Multiplexing possible – sensors adaptable to detect more than one target analyte.

Simplified Detection Process

Nanosensors (solution-based reagents) are added directly to target sample (no sample preparation is required).
The sample solution is read directly (no labeling or washing required).
Measurements will indicate whether or not the target analyte is in the sample solution.
Results are provided in under an hour, saving significant time and money (the process does not require a skilled technician or a laboratory setting).

Products in Development

In-Solution affinity-tagged protein Nanobiosensor

The His-tag is widely used in research labs as well as large-scale protein production facilities to aid recombinant protein purification. Currently, identification and monitoring of recombinant proteins involve laborious procedures such as gel electrophoresis. BioXene’s His-tag detection sensor is superior to existing products, allowing researchers and practitioners a much quicker, simpler method of measuring/monitoring His-tag recombinant proteins directly in-solution, without running gel electrophoresis. Current methods typically take several hours and require multiple procedures by skilled technicians; BioXene’s nanosensors will reduce the entire process to under an hour in a simple mix and measure procedure. In addition, the ability of the nanosensors to detect in-solution allows researchers to continually track and monitor the presence of the HIS-tag proteins in-solution throughout the entire protein purification process.